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Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq

Somatic cell nuclear transfer (SCNT) can reprogram terminally differentiated somatic cells into totipotent embryos, but with multiple defects. The nucleosome positioning, as an important epigenetic regulator for gene expression, is largely unexplored during SCNT embryonic development. Here, we mappe...

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Detalles Bibliográficos
Autores principales: Yang, Lingyue, Xu, Xiaocui, Xu, Ruimin, Chen, Chuan, Zhang, Xiaolei, Chen, Mo, Kou, Xiaochen, Zhao, Yanhong, Wang, Hong, Liu, Xiaoyu, Gao, Shaorong, Li, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287678/
https://www.ncbi.nlm.nih.gov/pubmed/35750045
http://dx.doi.org/10.1016/j.stemcr.2022.05.020