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Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq
Somatic cell nuclear transfer (SCNT) can reprogram terminally differentiated somatic cells into totipotent embryos, but with multiple defects. The nucleosome positioning, as an important epigenetic regulator for gene expression, is largely unexplored during SCNT embryonic development. Here, we mappe...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287678/ https://www.ncbi.nlm.nih.gov/pubmed/35750045 http://dx.doi.org/10.1016/j.stemcr.2022.05.020 |