Transcription factor-based direct conversion of human fibroblasts to functional astrocytes

Astrocytes are emerging key players in neurological disorders. However, their role in disease etiology is poorly understood owing to inaccessibility of primary human astrocytes. Pluripotent stem cell-derived cells fail to mimic age and due to their clonal origin do not mimic genetic heterogeneity of...

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Detalles Bibliográficos
Autores principales: Quist, Ella, Trovato, Francesco, Avaliani, Natalia, Zetterdahl, Oskar G., Gonzalez-Ramos, Ana, Hansen, Marita G., Kokaia, Merab, Canals, Isaac, Ahlenius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287681/
https://www.ncbi.nlm.nih.gov/pubmed/35750047
http://dx.doi.org/10.1016/j.stemcr.2022.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287681/
https://www.ncbi.nlm.nih.gov/pubmed/35750047
http://dx.doi.org/10.1016/j.stemcr.2022.05.015

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