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A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptors

Fc engineering efforts are increasingly being employed to modulate interaction of antibodies with variety of Fc receptors in an effort to improve the efficacy and safety of the therapeutic antibodies. Among the various Fc receptors, Fc gamma receptors (FcγRs) present on variety of immune cells are e...

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Detalles Bibliográficos
Autores principales: Nath, Nidhi, Godat, Becky, Flemming, Rod, Urh, Marjeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287719/
https://www.ncbi.nlm.nih.gov/pubmed/35842448
http://dx.doi.org/10.1038/s41598-022-15887-z