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The m6A reader YTHDF3-mediated PRDX3 translation alleviates liver fibrosis

Peroxiredoxin 3 (PRDX3) acts as a master regulator of mitochondrial oxidative stress and exerts hepatoprotective effects, but the role of PRDX3 in liver fibrosis is not well understood. N(6)-methyladenosine (m6A) is considered the most prevalent posttranscriptional modification of mRNA. This study a...

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Detalles Bibliográficos
Autores principales: Sun, Ruimin, Tian, Xinyao, Li, Yang, Zhao, Yan, Wang, Zhecheng, Hu, Yan, Zhang, Lijun, Wang, Yue, Gao, Dongyan, Zheng, Shusen, Yao, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287738/
https://www.ncbi.nlm.nih.gov/pubmed/35779442
http://dx.doi.org/10.1016/j.redox.2022.102378