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The m6A reader YTHDF3-mediated PRDX3 translation alleviates liver fibrosis
Peroxiredoxin 3 (PRDX3) acts as a master regulator of mitochondrial oxidative stress and exerts hepatoprotective effects, but the role of PRDX3 in liver fibrosis is not well understood. N(6)-methyladenosine (m6A) is considered the most prevalent posttranscriptional modification of mRNA. This study a...
Autores principales: | Sun, Ruimin, Tian, Xinyao, Li, Yang, Zhao, Yan, Wang, Zhecheng, Hu, Yan, Zhang, Lijun, Wang, Yue, Gao, Dongyan, Zheng, Shusen, Yao, Jihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287738/ https://www.ncbi.nlm.nih.gov/pubmed/35779442 http://dx.doi.org/10.1016/j.redox.2022.102378 |
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