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Formulation and evaluation of a smart drug delivery system of 5-fluorouracil for pH-sensitive chemotherapy

The conventional chemotherapeutic drugs have many side effects due to their non-selective tissue distribution, reduced drug concentration of the drug at the tumor site, and the drug resistance. To overcome these problems the chemotherapeutic agent should selectively accumulate the tumor site and sta...

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Detalles Bibliográficos
Autores principales: Cheralayikkal, Shamla, Manoj, K., Safna Hussan, K.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287813/
https://www.ncbi.nlm.nih.gov/pubmed/35855997
http://dx.doi.org/10.1016/j.heliyon.2022.e09926