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Quantitative modeling of pentose phosphate pathway response to oxidative stress reveals a cooperative regulatory strategy

Living cells use signaling and regulatory mechanisms to adapt to environmental stresses. Adaptation to oxidative stress involves the regulation of many enzymes in both glycolysis and pentose phosphate pathways (PPP), so as to support PPP-driven NADPH recycling for antioxidant defense. The underlying...

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Detalles Bibliográficos
Autores principales: Hurbain, Julien, Thommen, Quentin, Anquez, Francois, Pfeuty, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287814/
https://www.ncbi.nlm.nih.gov/pubmed/35856027
http://dx.doi.org/10.1016/j.isci.2022.104681