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Proton pump inhibitor in the prevention of upper gastrointestinal mucosal injury associated with dual antiplatelet therapy after coronary artery bypass grafting (DACAB-GI-2): study protocol for a randomized controlled trial

BACKGROUND: Dual antiplatelet therapy (DAPT) is recommended in secondary prevention after coronary artery bypass grafting (CABG), but it is inevitably associated with the risk of bleeding, of which gastrointestinal bleeding accounts for more than half. Proton pump inhibitors (PPIs) may increase the...

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Detalles Bibliográficos
Autores principales: Zhu, Yunpeng, Wang, Xiaojin, Yang, Yi, Liu, Lei, Zhao, Qiang, Yu, Lifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287869/
https://www.ncbi.nlm.nih.gov/pubmed/35840999
http://dx.doi.org/10.1186/s13063-022-06464-w