Proton export upregulates aerobic glycolysis

INTRODUCTION: Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect.” It is widely assumed that this is a consequence of the upregulation of glycolytic enzymes. Oncogenic drivers can incre...

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Detalles Bibliográficos
Autores principales: Russell, Shonagh, Xu, Liping, Kam, Yoonseok, Abrahams, Dominique, Ordway, Bryce, Lopez, Alex S., Bui, Marilyn M., Johnson, Joseph, Epstein, Tamir, Ruiz, Epifanio, Lloyd, Mark C., Swietach, Pawel, Verduzco, Daniel, Wojtkowiak, Jonathan, Gillies, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287933/
https://www.ncbi.nlm.nih.gov/pubmed/35840963
http://dx.doi.org/10.1186/s12915-022-01340-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287933/
https://www.ncbi.nlm.nih.gov/pubmed/35840963
http://dx.doi.org/10.1186/s12915-022-01340-0

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