Cargando…

Proton export upregulates aerobic glycolysis

INTRODUCTION: Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect.” It is widely assumed that this is a consequence of the upregulation of glycolytic enzymes. Oncogenic drivers can incre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Russell, Shonagh, Xu, Liping, Kam, Yoonseok, Abrahams, Dominique, Ordway, Bryce, Lopez, Alex S., Bui, Marilyn M., Johnson, Joseph, Epstein, Tamir, Ruiz, Epifanio, Lloyd, Mark C., Swietach, Pawel, Verduzco, Daniel, Wojtkowiak, Jonathan, Gillies, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287933/ https://www.ncbi.nlm.nih.gov/pubmed/35840963 http://dx.doi.org/10.1186/s12915-022-01340-0

Ejemplares similares

Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane
por: Epstein, Tamir, et al.
Publicado: (2014)

Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities
por: Ordway, Bryce, et al.
Publicado: (2020)

Causes and Consequences of Variable Tumor Cell Metabolism on Heritable Modifications and Tumor Evolution
por: Ordway, Bryce, et al.
Publicado: (2020)

Metabolic Profiling of healthy and cancerous tissues in 2D and 3D
por: Russell, Shonagh, et al.
Publicado: (2017)

Aerobic Glycolysis: Beyond Proliferation
por: Jones, William, et al.
Publicado: (2015)

Aerobic glycolysis, motility, and cytoskeletal remodeling
por: Verdone, James E, et al.
Publicado: (2015)

WWOX loss activates aerobic glycolysis
por: Abu-Remaileh, Muhannad, et al.
Publicado: (2014)

Extracellular Acidification Induces Lysosomal Dysregulation
por: Ordway, Bryce, et al.
Publicado: (2021)

Oncogenic virus-induced aerobic glycolysis and tumorigenesis
por: Yu, Li, et al.
Publicado: (2018)

Micromanaging aerobic respiration and glycolysis in cancer cells
por: Orang, Ayla V., et al.
Publicado: (2019)

The therapeutic implications of immunosuppressive tumor aerobic glycolysis
por: Reinfeld, Bradley I., et al.
Publicado: (2021)

Brain aerobic glycolysis and resilience in Alzheimer disease
por: Goyal, Manu S., et al.
Publicado: (2023)

Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited
por: Vazquez, Alexei, et al.
Publicado: (2010)

FLIP(L) is critical for aerobic glycolysis in hepatocellular carcinoma
por: Lei, Shixiong, et al.
Publicado: (2016)

Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
por: Feng, Jiao, et al.
Publicado: (2020)

Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma
por: Han, Wei, et al.
Publicado: (2020)

Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis
por: Ma, Lisi, et al.
Publicado: (2020)

Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts
por: Lee, Wen-Chih, et al.
Publicado: (2020)

Aerobic Glycolysis: A DeOxymoron of (Neuro)Biology
por: Schurr, Avital, et al.
Publicado: (2022)

Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
por: Pillai, Smitha, et al.
Publicado: (2022)

Hyperglycemia Enhances Immunosuppression and Aerobic Glycolysis of Pancreatic Cancer Through Upregulating Bmi1-UPF1-HK2 Pathway
por: Wu, Shihong, et al.
Publicado: (2022)

KITENIN promotes aerobic glycolysis through PKM2 induction by upregulating the c-Myc/hnRNPs axis in colorectal cancer
por: Varlı, Mücahit, et al.
Publicado: (2023)

Vascular measurements correlate with estrogen receptor status
por: Lloyd, Mark C, et al.
Publicado: (2014)

Role of aerobic glycolysis in genetically engineered mouse models of cancer
por: Dang, Chi V
Publicado: (2013)

The sweet trap in tumors: aerobic glycolysis and potential targets for therapy
por: Yu, Li, et al.
Publicado: (2016)

Aerobic glycolysis and high level of lactate in cancer metabolism and microenvironment
por: Jiang, Bo
Publicado: (2017)

Aerobic Glycolysis in the Retina: Functional Roles of Pyruvate Kinase Isoforms
por: Rajala, Raju V. S.
Publicado: (2020)

The influence of circadian rhythms and aerobic glycolysis in autism spectrum disorder
por: Vallée, Alexandre, et al.
Publicado: (2020)

Lactate as an Astroglial Signal Augmenting Aerobic Glycolysis and Lipid Metabolism
por: Horvat, Anemari, et al.
Publicado: (2021)

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer
por: Zhang, Xiujuan, et al.
Publicado: (2022)

Multifaceted roles of aerobic glycolysis and oxidative phosphorylation in hepatocellular carcinoma
por: Zhang, Ying, et al.
Publicado: (2023)

RFC2 promotes aerobic glycolysis and progression of colorectal cancer
por: Lou, Fuchen, et al.
Publicado: (2023)

Back to basic: Trials and tribulations of alkalizing agents in cancer
por: Gillies, Robert J., et al.
Publicado: (2022)

Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis
por: Tennessen, Jason M., et al.
Publicado: (2014)

Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease
por: Riwanto, Meliana, et al.
Publicado: (2016)

Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death
por: Li, Sainan, et al.
Publicado: (2017)

A Mathematical Analysis of Aerobic Glycolysis Triggered by Glucose Uptake in Cones
por: Camacho, Erika T., et al.
Publicado: (2019)

Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells
por: Liu, Yijun, et al.
Publicado: (2018)

Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice
por: Harris, Richard A., et al.
Publicado: (2019)

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense
por: Krejčová, Gabriela, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5g10miff18bj709jndnqh0go1b