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ASIC1α up-regulates MMP-2/9 expression to enhance mobility and proliferation of liver cancer cells via the PI3K/AKT/mTOR pathway

A major challenge in the treatment of liver cancer is that a large proportion of patients fail to achieve long-term disease control, with death from liver cancer cell migration and invasion. Acid-sensitive ion channel 1α (ASIC1α) is involved in the migration, invasion, and proliferation of liver can...

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Detalles Bibliográficos
Autores principales: Zhang, Yinci, Liang, Jiaojiao, Cao, Niandie, Gao, Jiafeng, Xie, Yinghai, Zhou, Shuping, Tang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287982/
https://www.ncbi.nlm.nih.gov/pubmed/35840921
http://dx.doi.org/10.1186/s12885-022-09874-w