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A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinflammatory capacity of macrophages
BACKGROUND: Cardiovascular diseases (CVDs) are a significant cause of mortality worldwide and are characterized by severe atherosclerosis (AS) in patients. However, the molecular mechanism of AS formation remains elusive. In the present study, we investigated the role of syndecan-4 (SDC4), a member...
Autores principales: | Hu, Jiaxin, Zhang, Ying, Hu, Liaoping, Chen, Haiting, Wu, Han, Chen, Jianzhou, Xie, Jun, Xu, Biao, Wei, Zhonghai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287986/ https://www.ncbi.nlm.nih.gov/pubmed/35842658 http://dx.doi.org/10.1186/s12967-022-03505-5 |
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