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Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathway

BACKGROUND: Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis. Therapeutic approaches targeting TGF-β1 and its downstream pathways are essential to inhibit liver fibrosis....

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Detalles Bibliográficos
Autores principales: Song, Xudong, Shi, Jiayi, Liu, Jieting, Liu, Yong, Yu, Yang, Qiu, Yufei, Cao, Zhiqin, Pan, Yu, Yuan, Xiaohuan, Chu, Yanhui, Wu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288003/
https://www.ncbi.nlm.nih.gov/pubmed/35842576
http://dx.doi.org/10.1186/s10020-022-00508-2