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P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

BACKGROUND: We previously identified four Alzheimer’s disease (AD) subgroups with increasingly higher cerebrospinal fluid (CSF) levels of tau phosphorylated at threonine 181 (p-tau). These subgroups included individuals across the cognitive spectrum, suggesting p-tau subgroups could reflect distinct...

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Detalles Bibliográficos
Autores principales: Wesenhagen, Kirsten E. J., Tijms, Betty M., Boonkamp, Lynn, Hoede, Patty L., Goossens, Julie, Dewit, Nele, Scheltens, Philip, Vanmechelen, Eugeen, Visser, Pieter Jelle, Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288016/
https://www.ncbi.nlm.nih.gov/pubmed/35841015
http://dx.doi.org/10.1186/s13195-022-01038-z