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Human monocytes differentiate into tumor-associated macrophages upon SKOV3 cells coculture and/or lysophosphatidic acid stimulation

BACKGROUND: Serous ovarian carcinoma is the most common type of ovarian carcinoma. Tumor-associated macrophages (TAMs) promote ovarian cancer progression. Most macrophages are generated by monocyte differentiation. Lysophosphatidic acid (LPA) levels are high in blood, tissues and ascites of patients...

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Detalles Bibliográficos
Autores principales: Feng, Ying, Xiao, Meizhu, Cao, Guangming, Liu, Hao, Li, Yanfang, Wang, Shuzhen, Zijtveld, Stan, Delvoux, Bert, Xanthoulea, Sofia, Romano, Andrea, Liu, Chongdong, Zhang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288080/
https://www.ncbi.nlm.nih.gov/pubmed/35842650
http://dx.doi.org/10.1186/s12950-022-00307-w