Allosteric Hotspots in the Main Protease of SARS-CoV-2

Inhibiting the main protease of SARS-CoV-2 is of great interest in tackling the COVID-19 pandemic caused by the virus. Most efforts have been centred on inhibiting the binding site of the enzyme. However, considering allosteric sites, distant from the active or orthosteric site, broadens the search...

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Detalles Bibliográficos
Autores principales: Strömich, Léonie, Wu, Nan, Barahona, Mauricio, Yaliraki, Sophia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288249/
https://www.ncbi.nlm.nih.gov/pubmed/35843284
http://dx.doi.org/10.1016/j.jmb.2022.167748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288249/
https://www.ncbi.nlm.nih.gov/pubmed/35843284
http://dx.doi.org/10.1016/j.jmb.2022.167748

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