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BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells

The pathogenesis of intervertebral disc degeneration (IDD) is still unclear. It has been shown that the pathological process of IDD is most closely related to inflammation of nucleus pulposus cells (NPCs), in which inflammatory factors play an important role. Exosomes are the main paracrine mediator...

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Detalles Bibliográficos
Autores principales: Xiao, Quan, Zhao, Zhe, Teng, Yun, Wu, Lungang, Wang, Jinlong, Xu, Hongjun, Chen, Sumei, Zhou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288351/
https://www.ncbi.nlm.nih.gov/pubmed/35855812
http://dx.doi.org/10.1155/2022/9896444