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BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
The pathogenesis of intervertebral disc degeneration (IDD) is still unclear. It has been shown that the pathological process of IDD is most closely related to inflammation of nucleus pulposus cells (NPCs), in which inflammatory factors play an important role. Exosomes are the main paracrine mediator...
Autores principales: | Xiao, Quan, Zhao, Zhe, Teng, Yun, Wu, Lungang, Wang, Jinlong, Xu, Hongjun, Chen, Sumei, Zhou, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288351/ https://www.ncbi.nlm.nih.gov/pubmed/35855812 http://dx.doi.org/10.1155/2022/9896444 |
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