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Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein A-I in corona formation

Nanoparticle elasticity is crucial in nanoparticles’ physiological fate, but how this occurs is largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity (45 kPa – 760 MPa) as models, we isolate the effects of nanoparticle elasticity...

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Detalles Bibliográficos
Autores principales: Li, Mingyang, Jin, Xinyang, Liu, Tao, Fan, Feng, Gao, Feng, Chai, Shuang, Yang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288426/
https://www.ncbi.nlm.nih.gov/pubmed/35842431
http://dx.doi.org/10.1038/s41467-022-31882-4