Cargando…
Electrostatic interactions between single arginine and phospholipids modulate physiological properties of sarcoplasmic reticulum Ca(2+)-ATPase
Arg324 of sarcoplasmic reticulum Ca(2+)-ATPase forms electrostatic interactions with the phosphate moiety of phospholipids in most reaction states, and a hydrogen bond with Tyr122 in other states. Using site-directed mutagenesis, we explored the functional roles of Arg324 interactions, especially th...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288429/ https://www.ncbi.nlm.nih.gov/pubmed/35842495 http://dx.doi.org/10.1038/s41598-022-16091-9 |