Electrostatic interactions between single arginine and phospholipids modulate physiological properties of sarcoplasmic reticulum Ca(2+)-ATPase

Arg324 of sarcoplasmic reticulum Ca(2+)-ATPase forms electrostatic interactions with the phosphate moiety of phospholipids in most reaction states, and a hydrogen bond with Tyr122 in other states. Using site-directed mutagenesis, we explored the functional roles of Arg324 interactions, especially th...

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Detalles Bibliográficos
Autores principales: Yamasaki, Kazuo, Daiho, Takashi, Yasuda, Satoshi, Danko, Stefania, Kawabe, Jun-ichi, Suzuki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288429/
https://www.ncbi.nlm.nih.gov/pubmed/35842495
http://dx.doi.org/10.1038/s41598-022-16091-9

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