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High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence

Secretory leukocyte protease inhibitor (SLPI) is a pleiotropic protein produced by healthy intestinal epithelial cells. SLPI regulates NF-κB activation, inhibits neutrophil proteases and has broad antimicrobial activity. Recently, increased SLPI expression was found in various types of carcinomas an...

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Detalles Bibliográficos
Autores principales: Nugteren, Sandrine, den Uil, Sjoerd H., Delis-van Diemen, Pien M., Simons-Oosterhuis, Ytje, Lindenbergh-Kortleve, Dicky J., van Haaften, Daniëlle H., Stockmann, Hein B. A. C., Sanders, Joyce, Meijer, Gerrit A., Fijneman, Remond J. A., Samsom, Janneke N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288430/
https://www.ncbi.nlm.nih.gov/pubmed/35842496
http://dx.doi.org/10.1038/s41598-022-16427-5