Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models

Myelodysplastic syndromes (MDS) are characterized by daunting genetic heterogeneity and a high risk of leukemic transformation, which presents great challenges for clinical treatment. To identify new chemicals for MDS, we screened a panel of FDA-approved drugs and verified the neutrophil hyperplasia...

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Detalles Bibliográficos
Autores principales: Li, Xuexiao, Wang, Luping, Qin, Xun, Chen, Xiaohui, Li, Li, Huang, Zhibin, Zhang, Wenqing, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288432/
https://www.ncbi.nlm.nih.gov/pubmed/35842445
http://dx.doi.org/10.1038/s41420-022-01121-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288432/
https://www.ncbi.nlm.nih.gov/pubmed/35842445
http://dx.doi.org/10.1038/s41420-022-01121-2

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