Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models

We have previously established a novel mouse model of lung fibrosis based on Adeno-associated virus (AAV)-mediated pulmonary overexpression of TGFβ1. Here, we provide an in-depth characterization of phenotypic and transcriptomic changes (mRNA and miRNA) in a head-to-head comparison with Bleomycin-in...

Descripción completa

Detalles Bibliográficos
Autores principales: Strobel, Benjamin, Klein, Holger, Leparc, Germán, Stierstorfer, Birgit E., Gantner, Florian, Kreuz, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288451/
https://www.ncbi.nlm.nih.gov/pubmed/35842487
http://dx.doi.org/10.1038/s41598-022-16344-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288451/
https://www.ncbi.nlm.nih.gov/pubmed/35842487
http://dx.doi.org/10.1038/s41598-022-16344-7

Ejemplares similares