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Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models

We have previously established a novel mouse model of lung fibrosis based on Adeno-associated virus (AAV)-mediated pulmonary overexpression of TGFβ1. Here, we provide an in-depth characterization of phenotypic and transcriptomic changes (mRNA and miRNA) in a head-to-head comparison with Bleomycin-in...

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Detalles Bibliográficos
Autores principales:	Strobel, Benjamin, Klein, Holger, Leparc, Germán, Stierstorfer, Birgit E., Gantner, Florian, Kreuz, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288451/ https://www.ncbi.nlm.nih.gov/pubmed/35842487 http://dx.doi.org/10.1038/s41598-022-16344-7

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