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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique shape maintained by a complex cytoskeleton, which becomes disrupted in glomerular disease resulting in defective filtration and albuminuria. L...

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Detalles Bibliográficos
Autores principales: Mason, William J., Jafree, Daniyal J., Pomeranz, Gideon, Kolatsi-Joannou, Maria, Rottner, Antje K., Pacheco, Sabrina, Moulding, Dale A., Wolf, Anja, Kupatt, Christian, Peppiatt-Wildman, Claire, Papakrivopoulou, Eugenia, Riley, Paul R., Long, David A., Vasilopoulou, Elisavet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288454/
https://www.ncbi.nlm.nih.gov/pubmed/35842494
http://dx.doi.org/10.1038/s41598-022-16287-z