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PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity

The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described, acting as an inhibitor of tissue plasminogen activator and urokinase-type plasminogen activator, impacting fibrinolysis. Recent studies have revealed a pro-tumorigenic role of PAI-1 in human cancers, via the r...

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Detalles Bibliográficos
Autores principales: Furuya, Hideki, Sasaki, Yuka, Chen, Runpu, Peres, Rafael, Hokutan, Kanani, Murakami, Kaoru, Kim, Nari, Chan, Owen T. M., Pagano, Ian, Dyrskjøt, Lars, Jensen, Jørgen B., Malmstrom, Per-Uno, Segersten, Ulrika, Sun, Yijun, Arab, Abolfazl, Goodarzi, Hani, Goodison, Steve, Rosser, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288475/
https://www.ncbi.nlm.nih.gov/pubmed/35842542
http://dx.doi.org/10.1038/s41598-022-16518-3