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PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity
The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described, acting as an inhibitor of tissue plasminogen activator and urokinase-type plasminogen activator, impacting fibrinolysis. Recent studies have revealed a pro-tumorigenic role of PAI-1 in human cancers, via the r...
Autores principales: | Furuya, Hideki, Sasaki, Yuka, Chen, Runpu, Peres, Rafael, Hokutan, Kanani, Murakami, Kaoru, Kim, Nari, Chan, Owen T. M., Pagano, Ian, Dyrskjøt, Lars, Jensen, Jørgen B., Malmstrom, Per-Uno, Segersten, Ulrika, Sun, Yijun, Arab, Abolfazl, Goodarzi, Hani, Goodison, Steve, Rosser, Charles J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288475/ https://www.ncbi.nlm.nih.gov/pubmed/35842542 http://dx.doi.org/10.1038/s41598-022-16518-3 |
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