Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

Obesity and diabetes are well known risk factors for nonalcoholic fatty liver disease (NAFLD), but the genetic factors contributing to the development of NAFLD remain poorly understood. Here we describe two semi-dominant allelic missense mutations (Oily and Carboniferous) of Predicted gene 4951 (Gm4...

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Detalles Bibliográficos
Autores principales: Zhang, Zhao, Xun, Yu, Rong, Shunxing, Yan, Lijuan, SoRelle, Jeffrey A., Li, Xiaohong, Tang, Miao, Keller, Katie, Ludwig, Sara, Moresco, Eva Marie Y., Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288484/
https://www.ncbi.nlm.nih.gov/pubmed/35842425
http://dx.doi.org/10.1038/s41467-022-31812-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288484/
https://www.ncbi.nlm.nih.gov/pubmed/35842425
http://dx.doi.org/10.1038/s41467-022-31812-4

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