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SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism

Localized in the mitochondria, SIRT4 is a nicotinamide adenine dinucleotide (NAD +) -dependent adenosine diphosphate (ADP) -ribosyltransferase and is one of the least characterized members of the sirtuin family. Although it is well known that it shows deacetylase activity for energy metabolism, litt...

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Detalles Bibliográficos
Autores principales: Cai, Guohao, Ge, Zhuhui, Xu, Yunqiu, Cai, Liangliang, Sun, Pingliang, Huang, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288510/
https://www.ncbi.nlm.nih.gov/pubmed/35842463
http://dx.doi.org/10.1038/s41598-022-16610-8