Cargando…
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
Localized in the mitochondria, SIRT4 is a nicotinamide adenine dinucleotide (NAD +) -dependent adenosine diphosphate (ADP) -ribosyltransferase and is one of the least characterized members of the sirtuin family. Although it is well known that it shows deacetylase activity for energy metabolism, litt...
Autores principales: | Cai, Guohao, Ge, Zhuhui, Xu, Yunqiu, Cai, Liangliang, Sun, Pingliang, Huang, Guoyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288510/ https://www.ncbi.nlm.nih.gov/pubmed/35842463 http://dx.doi.org/10.1038/s41598-022-16610-8 |
Ejemplares similares
-
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism
por: Chen, Zhouxun, et al.
Publicado: (2019) -
SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy
por: Yin, Jie, et al.
Publicado: (2023) -
Control of Glutamine Metabolism By the Tumor Suppressor Rb
por: Reynolds, Miriam R., et al.
Publicado: (2013) -
Oncogenes and Tumor Suppressors Regulate Glutamine Metabolism in Cancer Cells
por: Kim, Min Hyun, et al.
Publicado: (2013) -
SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis
por: Zhu, Yueming, et al.
Publicado: (2014)