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The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation

To investigate electrical synapse formation in vivo we used forward genetics to disrupt genes affecting Mauthner cell electrical synapses in larval zebrafish. We identify the disconnect2 ( dis2 ) mutation for its failure to localize neural gap junction channels at electrical synapses. We mapped this...

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Detalles Bibliográficos
Autores principales: Michel, Jennifer Carlisle, Lasseigne, Abagael M., Marsh, Audrey J., Miller, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288654/
https://www.ncbi.nlm.nih.gov/pubmed/35855444
http://dx.doi.org/10.17912/micropub.biology.000593