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Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?

BACKGROUND: Levels of the biomarkers amyloid-β 1–42 (Aβ42), tau and phosphorylated tau (p-tau) are decreased in the cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). The mechanism behind this is unknown, but one potential explanation is dilution by excessive...

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Detalles Bibliográficos
Autores principales: Lidén, Simon, Farahmand, Dan, Laurell, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288679/
https://www.ncbi.nlm.nih.gov/pubmed/35843939
http://dx.doi.org/10.1186/s12987-022-00353-9