Cargando…

Prostaglandin E1 reduces apoptosis and improves the homing of mesenchymal stem cells in pulmonary arterial hypertension by regulating hypoxia-inducible factor 1 alpha

BACKGROUND: Pulmonary arterial hypertension (PAH) is associated with oxidative stress and affects the survival and homing of transplanted mesenchymal stem cells (MSCs) as well as cytokine secretion by the MSCs, thereby altering their therapeutic potential. In this study, we preconditioned the MSCs w...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, De-Tian, Tuo, Lei, Bai, Xiao, Bing, Wei-Dong, Qu, Qing-Xi, Zhao, Xin, Song, Guang-Min, Bi, Yan-Wen, Sun, Wen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288720/
https://www.ncbi.nlm.nih.gov/pubmed/35842683
http://dx.doi.org/10.1186/s13287-022-03011-x