Determinants of Spike infectivity, processing, and neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2

SARS-CoV-2 Omicron rapidly outcompeted other variants and currently dominates the COVID-19 pandemic. Its enhanced transmission and immune evasion are thought to be driven by numerous mutations in the Omicron Spike protein. Here, we systematically introduced BA.1 and/or BA.2 Omicron Spike mutations i...

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Detalles Bibliográficos
Autores principales: Pastorio, Chiara, Zech, Fabian, Noettger, Sabrina, Jung, Christoph, Jacob, Timo, Sanderson, Theo, Sparrer, Konstantin M.J., Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289044/
https://www.ncbi.nlm.nih.gov/pubmed/35931073
http://dx.doi.org/10.1016/j.chom.2022.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289044/
https://www.ncbi.nlm.nih.gov/pubmed/35931073
http://dx.doi.org/10.1016/j.chom.2022.07.006

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