Nutritional and Metabolic Factors, Ethanol and Cholesterol, Interact With Calcium-Dependent N-Methyl-D-Aspartate Receptor Inhibition by Tricyclic Antidepressants

It is known that overexpression of N-methyl-D-aspartate receptors (NMDARs) contributes to central sensitization and development of neuropathic pain. Tricyclic antidepressants (TCAs), amitriptyline (ATL), and desipramine (DES) exhibit analgetic anti-NMDAR activity and are commonly utilized for pain t...

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Detalles Bibliográficos
Autores principales: Boikov, Sergei I., Sibarov, Dmitry A., Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289099/
https://www.ncbi.nlm.nih.gov/pubmed/35860312
http://dx.doi.org/10.3389/fncel.2022.946426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289099/
https://www.ncbi.nlm.nih.gov/pubmed/35860312
http://dx.doi.org/10.3389/fncel.2022.946426

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