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Paeoniflorin Ameliorates BiPN by Reducing IL6 Levels and Regulating PARKIN-Mediated Mitochondrial Autophagy

BACKGROUND: Bortezomib-induced peripheral neuropathy (BiPN) is a common complication of multiple myeloma (MM) treatment that seriously affects the quality of life of patients. The purpose of the present study was to explore the therapeutic effect of paeoniflorin on BiPN and its possible mechanism. M...

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Detalles Bibliográficos
Autores principales: Sun, Runjie, Liu, Jiang, Yu, Manya, Xia, Mengting, Zhang, Yanyu, Sun, Xiaoqi, Xu, Yunsheng, Cui, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289176/
https://www.ncbi.nlm.nih.gov/pubmed/35860525
http://dx.doi.org/10.2147/DDDT.S369111