Cargando…

Paeoniflorin Ameliorates BiPN by Reducing IL6 Levels and Regulating PARKIN-Mediated Mitochondrial Autophagy

BACKGROUND: Bortezomib-induced peripheral neuropathy (BiPN) is a common complication of multiple myeloma (MM) treatment that seriously affects the quality of life of patients. The purpose of the present study was to explore the therapeutic effect of paeoniflorin on BiPN and its possible mechanism. M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Runjie, Liu, Jiang, Yu, Manya, Xia, Mengting, Zhang, Yanyu, Sun, Xiaoqi, Xu, Yunsheng, Cui, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289176/ https://www.ncbi.nlm.nih.gov/pubmed/35860525 http://dx.doi.org/10.2147/DDDT.S369111

Ejemplares similares

PB1972: PAEONIFLORIN ALLEVIATES BIPN BY REDUCING IL6 LEVELS AND MODULATING PARKIN-MEDIATED MITOPHAGY
por: Sun, R., et al.
Publicado: (2022)

A novel circRNA-miRNA-mRNA network revealed exosomal circ-ATP10A as a biomarker for multiple myeloma angiogenesis
por: Yu, Manya, et al.
Publicado: (2021)

Parkin Regulates Mitochondrial Autophagy After Myocardial Infarction in Rats
por: Wu, Li, et al.
Publicado: (2016)

Baicalin regulates autophagy to interfere with small intestinal acute graft-versus-host disease
por: Sun, Xiaoqi, et al.
Publicado: (2022)

Crystal, magnetic, and electronic structures, and properties of new BaMnPnF (Pn = As, Sb, Bi)
por: Saparov, Bayrammurad, et al.
Publicado: (2013)

CORRIGENDUM: Crystal, magnetic, and electronic structures, and properties of new BaMnPnF (Pn = As, Sb, Bi)
por: Saparov, Bayrammurad, et al.
Publicado: (2013)

Actinide–Pnictide (An−Pn) Bonds Spanning Non‐Metal, Metalloid, and Metal Combinations (An=U, Th; Pn=P, As, Sb, Bi)
por: Rookes, Thomas M., et al.
Publicado: (2017)

Paeoniflorin suppresses allergic and inflammatory responses by promoting autophagy in rats with urticaria
por: Guo, Jing, et al.
Publicado: (2021)

Paeoniflorin inhibits proliferation and promotes autophagy and apoptosis of sweat gland cells
por: Xu, Yuan, et al.
Publicado: (2022)

Paeoniflorin Ameliorates Hyperprolactinemia-Induced Inhibition of Osteoblastogenesis by Suppressing the NF-κB Signaling Pathway
por: Sun, Xiaohong, et al.
Publicado: (2022)

Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviors in mice
por: Li, Jianwei, et al.
Publicado: (2016)

Paeoniflorin ameliorates acute necrotizing pancreatitis and pancreatitis-induced acute renal injury
por: Wang, Peng, et al.
Publicado: (2016)

Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson’s Disease via Parkin
por: Ma, Hao-Jie, et al.
Publicado: (2020)

Rapid determination of paeoniflorin
por: Wiwanitkit, Viroj
Publicado: (2010)

Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain
por: Zhou, Danli, et al.
Publicado: (2019)

Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling
por: He, Zhu-qing, et al.
Publicado: (2022)

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
por: Narendra, Derek, et al.
Publicado: (2008)

Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation
por: Ma, Zemeng, et al.
Publicado: (2023)

Exosomal circRNA as a novel potential therapeutic target for multiple myeloma-related myocardial damage
por: Sun, Runjie, et al.
Publicado: (2021)

Paeoniflorin Ameliorates Macrophage Infiltration and Activation by Inhibiting the TLR4 Signaling Pathway in Diabetic Nephropathy
por: Shao, Yun-xia, et al.
Publicado: (2019)

Paeoniflorin ameliorates ulcerative colitis by modulating the dendritic cell-mediated T(H)17/T(reg) balance
por: Zheng, Kai, et al.
Publicado: (2020)

Paeoniflorin ameliorates glycemic variability-induced oxidative stress and platelet activation in HUVECs and DM rats
por: Huang, Ye, et al.
Publicado: (2020)

Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-Like Cardiomyocytes
por: Ren, Xuecong, et al.
Publicado: (2017)

DdCBE-mediated mitochondrial base editing in human 3PN embryos
por: Chen, Xiaoxu, et al.
Publicado: (2022)

NCLEX-PN®
por: Gardner, Wilda
Publicado: (2017)

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
por: Matsuda, Noriyuki, et al.
Publicado: (2010)

Bismuth Amides Mediate Facile and Highly Selective Pn–Pn Radical‐Coupling Reactions (Pn=N, P, As)
por: Oberdorf, Kai, et al.
Publicado: (2021)

Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
por: Hoffmann-Conaway, Sheila, et al.
Publicado: (2020)

Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
por: Bian, Minjuan, et al.
Publicado: (2012)

Effects of glycyrrhizin on the pharmacokinetics of paeoniflorin in rats and its potential mechanism
por: Sun, Hongjuan, et al.
Publicado: (2019)

New Monoterpene Glycoside Paeoniflorin Derivatives as NO and IL-1β Inhibitors: Synthesis and Biological Evaluation
por: Chen, Yongjie, et al.
Publicado: (2023)

Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2014)

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2012)

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
por: Sarraf, Shireen A., et al.
Publicado: (2013)

Mitochondrial quality control beyond PINK1/Parkin
por: von Stockum, Sophia, et al.
Publicado: (2018)

Multiple Roles of Paeoniflorin in Alzheimer's Disease
por: Meng, Zeyu, et al.
Publicado: (2022)

Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy
por: Zhang, Yanyu, et al.
Publicado: (2020)

Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function
por: Hwang, Chul Ju, et al.
Publicado: (2016)

Atg1-mediated autophagy suppresses tissue degeneration in pink1/parkin mutants by promoting mitochondrial fission in Drosophila
por: Ma, Peng, et al.
Publicado: (2018)

Effect and Mechanism of PINK1/Parkin-Mediated Mitochondrial Autophagy in Rat Lung Injury Induced by Nano Lanthanum Oxide
por: Chen, Chunyu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rcbta9k25og6j9g0v696qsvo54