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Factors Affecting the Expression of Recombinant Protein and Improvement Strategies in Chinese Hamster Ovary Cells

Recombinant therapeutic proteins (RTPs) are important parts of biopharmaceuticals. Chinese hamster ovary cells (CHO) have become the main cell hosts for the production of most RTPs approved for marketing because of their high-density suspension growth characteristics, and similar human post-translat...

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Detalles Bibliográficos
Autores principales: Li, Zheng-Mei, Fan, Zhen-Lin, Wang, Xiao-Yin, Wang, Tian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289362/
https://www.ncbi.nlm.nih.gov/pubmed/35860329
http://dx.doi.org/10.3389/fbioe.2022.880155