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AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics

Mitochondrial dysfunction is a salient feature of myocardial ischemia/reperfusion injury (MIRI), while the potential mechanism of mitochondrial dynamics disorder remains unclear. This study sought to explore whether activation of Adenosine monophosphate-activated protein kinase (AMPK) could alleviat...

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Detalles Bibliográficos
Autores principales: Du, Jingxia, Li, Hongchao, Song, Jingjing, Wang, Tingting, Dong, Yibo, Zhan, An, Li, Yan, Liang, Gaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289369/
https://www.ncbi.nlm.nih.gov/pubmed/35860026
http://dx.doi.org/10.3389/fphar.2022.862204