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Cardiomyocyte Cell-Cycle Regulation in Neonatal Large Mammals: Single Nucleus RNA-Sequencing Data Analysis via an Artificial-Intelligence–Based Pipeline

Adult mammalian cardiomyocytes have very limited capacity to proliferate and repair the myocardial infarction. However, when apical resection (AR) was performed in pig hearts on postnatal day (P) 1 (AR(P1)) and acute myocardial infarction (MI) was induced on P28 (MI(P28)), the animals recovered with...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh, Wei, Yuhua, Nakada, Yuji, Zhou, Yang, Zhang, Jianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289371/
https://www.ncbi.nlm.nih.gov/pubmed/35860330
http://dx.doi.org/10.3389/fbioe.2022.914450