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A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer’s Disease by Dual Inhibition of Acetylcholinesterase and Inflammation

BACKGROUNDS: Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease. The treatment of AD through multiple pathological targets may generate therapeutic efficacy better. The multifunctional molecules that simultaneously hit several pathological targets have been of great interest in t...

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Detalles Bibliográficos
Autores principales: Liu, Chan, Sang, Zhipei, Pan, Hong, Wu, Qin, Qiu, Yu, Shi, Jingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289467/
https://www.ncbi.nlm.nih.gov/pubmed/35860673
http://dx.doi.org/10.3389/fnagi.2022.922650