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Eicosanoid-Activated PPARα Inhibits NFκB-Dependent Bacterial Clearance During Post-Influenza Superinfection

Secondary bacterial infection (superinfection) post influenza is a serious clinical complication often leading to pneumonia and death. Eicosanoids are bioactive lipid mediators that play critical roles in the induction and resolution of inflammation. CYP450 lipid metabolites are anti-inflammatory li...

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Detalles Bibliográficos
Autores principales: Lucarelli, Ronald, Gorrochotegui-Escalante, Norma, Taddeo, Jessica, Buttaro, Bettina, Beld, Joris, Tam, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289478/
https://www.ncbi.nlm.nih.gov/pubmed/35860381
http://dx.doi.org/10.3389/fcimb.2022.881462