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Eicosanoid-Activated PPARα Inhibits NFκB-Dependent Bacterial Clearance During Post-Influenza Superinfection
Secondary bacterial infection (superinfection) post influenza is a serious clinical complication often leading to pneumonia and death. Eicosanoids are bioactive lipid mediators that play critical roles in the induction and resolution of inflammation. CYP450 lipid metabolites are anti-inflammatory li...
Autores principales: | Lucarelli, Ronald, Gorrochotegui-Escalante, Norma, Taddeo, Jessica, Buttaro, Bettina, Beld, Joris, Tam, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289478/ https://www.ncbi.nlm.nih.gov/pubmed/35860381 http://dx.doi.org/10.3389/fcimb.2022.881462 |
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