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Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Varicella‐Zoster virus (VZV) causes chickenpox and shingles. Although the infection is associated with severe morbidity in some individuals, molecular mechanisms that determine innate immune responses remain poorly defined. We found that the cGAS/STING DNA sensing pathway was required for type I int...

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Detalles Bibliográficos
Autores principales: Hertzog, Jonny, Zhou, Wen, Fowler, Gerissa, Rigby, Rachel E, Bridgeman, Anne, Blest, Henry TW, Cursi, Chiara, Chauveau, Lise, Davenne, Tamara, Warner, Benjamin E, Kinchington, Paul R, Kranzusch, Philip J, Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289529/
https://www.ncbi.nlm.nih.gov/pubmed/35670106
http://dx.doi.org/10.15252/embj.2021109217