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Effect of donepezil for dementia prevention in Parkinson's disease with severe hyposmia (The DASH-PD study): A randomized long-term placebo-controlled trial

BACKGROUND: Dementia greatly contributes to poor prognosis in patients with Parkinson's disease (PD). We previously reported that severe olfactory dysfunction may be a good predictor of Parkinson's disease dementia (PDD). In this trial, we investigated whether early administration of donep...

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Detalles Bibliográficos
Autores principales: Baba, Toru, Takeda, Atsushi, Murakami, Aya, Koga, Tadashi, Isomura, Tatsuya, Mori, Etsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289637/
https://www.ncbi.nlm.nih.gov/pubmed/35860451
http://dx.doi.org/10.1016/j.eclinm.2022.101571