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MLH1, BRAF and p53 – searching for significant markers to predict evolution towards adenocarcinoma in colonic sessile serrated lesions
Background and Aim: Colonic serrated lesions are premalignant lesions, using an alternative malignization pathway, including multiple genetic and epigenetic alterations, as: mismatch repair deficiency due to MutL homolog 1 (MLH1) promoter methylation, tumor protein p53 (TP53) mutations, activating m...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289700/ https://www.ncbi.nlm.nih.gov/pubmed/35673816 http://dx.doi.org/10.47162/RJME.62.4.09 |