MLH1, BRAF and p53 – searching for significant markers to predict evolution towards adenocarcinoma in colonic sessile serrated lesions

Background and Aim: Colonic serrated lesions are premalignant lesions, using an alternative malignization pathway, including multiple genetic and epigenetic alterations, as: mismatch repair deficiency due to MutL homolog 1 (MLH1) promoter methylation, tumor protein p53 (TP53) mutations, activating m...

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Detalles Bibliográficos
Autores principales: Răduţă, Diana, Dincă, Octavian Marius, Micu, Gianina Viorica, Nichita, Luciana, Cioplea, Mirela Daniela, Buşcă, Radu Mihai, Ardeleanu, Raluca, Mateescu, Radu Bogdan, Benguş, Andreea, Zurac, Sabina Andrada, Popp, Cristiana Gabriela, Vlădan, George Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289700/
https://www.ncbi.nlm.nih.gov/pubmed/35673816
http://dx.doi.org/10.47162/RJME.62.4.09

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