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Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a

Exosomes derived from mesenchymal stem cell (MSC) alleviate kidney damage through autophagy. This study determined whether MSCs relieve renal fibrosis and inhibit autophagy by exosome transfer of miRNA-122a. The gene expression involved in the mTOR signaling pathway and autophagy was assessed in TGF...

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Detalles Bibliográficos
Autores principales: Li, Dawei, Qu, Junwen, Yuan, Xiaodong, Zhuang, Shaoyong, Wu, Haoyu, Chen, Ruoyang, Wu, Jiajin, Zhang, Ming, Ying, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289760/
https://www.ncbi.nlm.nih.gov/pubmed/35859725
http://dx.doi.org/10.1155/2022/1981798