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An accurate prediction model of digenic interaction for estimating pathogenic gene pairs of human diseases

Increasing evidence shows that genetic interaction across the entire genome may explain a non-trivial fraction of genetic diseases. Digenic interaction is the simplest manifestation of genetic interaction among genes. However, systematic exploration of digenic interactive effects on the whole genome...

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Detalles Bibliográficos
Autores principales: Yuan, Yangyang, Zhang, Liubin, Long, Qihan, Jiang, Hui, Li, Miaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289819/
https://www.ncbi.nlm.nih.gov/pubmed/35891796
http://dx.doi.org/10.1016/j.csbj.2022.07.011